Comprehensive evaluation of risk factors for the development and complications of chemotherapy-induced febrile neutropenia
نویسندگان
چکیده
Febrile neutropenia is a serious adverse effect of chemotherapy. It can lead to complications and death, as well delays in treatment, chemotherapy dose reductions, compromised treatment efficacy, reduced survival. The assessment the patient-related risk factors plays significant role prevention febrile its complications. In case intermediate-risk chemotherapy, contribute estimation an overall timely planning primary prophylaxis using growth factors. Patients presenting with undergo detailed initial for so that appropriate be selected. Recommendations given by guidelines outline classification use validated tools makes it possible optimize each patient reduce morbidity mortality due neutropenia.
منابع مشابه
Chemotherapy induced febrile neutropenia: management and prevention.
chemotherapy remains the cornerstone of cancer therapy. In most cases bone marrow suppression represents the doselimiting toxicity of these drugs. Druginduced DNA damage at the level of bone marrow progenitor cells results in a fall in circulating neutrophil count. Patients with neutropenia are at increased risk of infection and sepsis.1 The timing of neutropenia is generally predictable; it ty...
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ژورنال
عنوان ژورنال: Srpski Arhiv Za Celokupno Lekarstvo
سال: 2022
ISSN: ['0370-8179', '2406-0895']
DOI: https://doi.org/10.2298/sarh211109054d